The median annual wage for Nurse Practitioners in Sioux Falls, SD-MN is $130,580 (May 2024 BLS OES). The mean (average) is $124,890.
Pay spans roughly $102,710 at the 10th percentile to $155,060 at the 90th, so experience and specialisation move this figure a lot. At the median that is about $62.78 per hour. An estimated 470 people work as nurse practitioners in Sioux Falls, SD-MN.
| Median (annual) | $130,580 |
| Mean (annual) | $124,890 |
| Median (hourly) | $62.78 |
| 10th percentile | $102,710 |
| 90th percentile | $155,060 |
| Employment | 470 |
Updated 2026-07-23.
Source: BLS OES May 2024 — bls.gov/oes. Checked 2026-07-23.