The median annual wage for Registered Nurses in Sioux Falls, SD-MN is $68,890 (May 2024 BLS OES). The mean (average) is $71,060.
Pay spans roughly $51,980 at the 10th percentile to $92,850 at the 90th, so experience and specialisation move this figure a lot. At the median that is about $33.12 per hour. An estimated 7,480 people work as registered nurses in Sioux Falls, SD-MN.
| Median (annual) | $68,890 |
| Mean (annual) | $71,060 |
| Median (hourly) | $33.12 |
| 10th percentile | $51,980 |
| 90th percentile | $92,850 |
| Employment | 7,480 |
Updated 2026-07-23.
Source: BLS OES May 2024 — bls.gov/oes. Checked 2026-07-23.