The median annual wage for Registered Nurses in Spartanburg, SC is $79,550 (May 2024 BLS OES). The mean (average) is $81,380.
Pay spans roughly $67,780 at the 10th percentile to $97,950 at the 90th, so experience and specialisation move this figure a lot. At the median that is about $38.25 per hour. An estimated 4,660 people work as registered nurses in Spartanburg, SC.
| Median (annual) | $79,550 |
| Mean (annual) | $81,380 |
| Median (hourly) | $38.25 |
| 10th percentile | $67,780 |
| 90th percentile | $97,950 |
| Employment | 4,660 |
Updated 2026-07-23.
Source: BLS OES May 2024 — bls.gov/oes. Checked 2026-07-23.