The median annual wage for Registered Nurses in South Carolina is $79,900 (May 2024 BLS OES). The mean (average) is $84,930.
Pay spans roughly $64,200 at the 10th percentile to $102,040 at the 90th, so experience and specialisation move this figure a lot. At the median that is about $38.41 per hour. An estimated 50,300 people work as registered nurses in South Carolina.
| Median (annual) | $79,900 |
| Mean (annual) | $84,930 |
| Median (hourly) | $38.41 |
| 10th percentile | $64,200 |
| 90th percentile | $102,040 |
| Employment | 50,300 |
Updated 2026-07-23.
Source: BLS OES May 2024 — bls.gov/oes. Checked 2026-07-23.