The median annual wage for Registered Nurses in Florence, SC is $80,220 (May 2024 BLS OES). The mean (average) is $96,840.
Pay spans roughly $63,950 at the 10th percentile to $165,610 at the 90th, so experience and specialisation move this figure a lot. At the median that is about $38.57 per hour. An estimated 3,060 people work as registered nurses in Florence, SC.
| Median (annual) | $80,220 |
| Mean (annual) | $96,840 |
| Median (hourly) | $38.57 |
| 10th percentile | $63,950 |
| 90th percentile | $165,610 |
| Employment | 3,060 |
Updated 2026-07-23.
Source: BLS OES May 2024 — bls.gov/oes. Checked 2026-07-23.