The median annual wage for Registered Nurses in Columbia, SC is $80,100 (May 2024 BLS OES). The mean (average) is $84,870.
Pay spans roughly $64,890 at the 10th percentile to $104,390 at the 90th, so experience and specialisation move this figure a lot. At the median that is about $38.51 per hour. An estimated 9,800 people work as registered nurses in Columbia, SC.
| Median (annual) | $80,100 |
| Mean (annual) | $84,870 |
| Median (hourly) | $38.51 |
| 10th percentile | $64,890 |
| 90th percentile | $104,390 |
| Employment | 9,800 |
Updated 2026-07-23.
Source: BLS OES May 2024 — bls.gov/oes. Checked 2026-07-23.